Just block them everywhere you can and ignore them when you can't or - when they're too annoying - close whatever medium tried to push the bulshytt [1] on you. They're trying to influence you and the more you show you're annoyed, the more they notice they've succeeded in reaching you.
Block and cover [2], block and cover. For the rest, live on.
[1] https://anathem.fandom.com/wiki/Bulshytt
[2] Yes, I sometimes just cover them with my hand if I happen to use a device without functional content blocking.