I’m a JS/TS dev (and fan) I don’t think either is a replacement for Python. They are not standalone languages but require some runtime to interact with the world (DOM or Node.js etc) which have limited capabilities for interacting with the system - their focus is network services. It’s not that inaccurate to say that JS is just API for a C++ app. :)

Now if .NET was still not so embedded in the Windows ecosystem that would be very interesting to me to jump from TS. As it is I am learning Go instead.

My money would be on Go and Rust. Most of the major downsides of either language go away if you let the agent write almost all of the code

Go might have the advantage because it's easier to read outside the IDE

I feel like the moment for typescript taking over has come and gone. It also became way more complicated than necessary and that limits its appeal compared to python (not to say python doesn’t have problems of its own)

Interesting. Can you please elaborate more? Is it due to the combination of popular foundation (js) and the addition of strong typing? The runtime environment differences? The ease of integration with other languages / tools?

Interesting -- I still think that Python is an easier onramp than TypeScript for new developers. But given the popularity and depth of JavaScript, and the clear advantages (and popularity) of TypeScript in serious development, that's not a bad prediction.