> Oh, so you expect to change their culture and their value system
What do you mean culture and value system? You think isolation and nuclear weapons are parts of the Iranian culture????
And yes, Iran had multiple bouts of reformer presidents. Reformer within the limits of what the Supreme Leader would allow of course, but there is still a massive gulf of difference between them and the hardliners. A few years of visible economic development under reformers would have nudged things in the reconciliation direction.
Again, yanking the deal, even before the current strikes during negotiations, ensures that Iran will never fully trust the US. So realistically, what other choices do they have other than procure nuclear weapons for protection?
You said that "closer economic cooperation and trade" might lead to "(relative) reformers would be in power". Westerners "reforming" other cultures has not been fashionable for about half a century.