> you have to identify which is which somehow

The _routing_ system does. You have the same problem if you have multiple public IPs on a machine. Your local routing will not automatically return packets back through the address they came to. They will go to the _default_ route. So if you have this configuration you need to setup either the routing tables or the firewall to re-route packets "back out" the proper interface or IP address.

This is strictly a routing problem and not an addressing problem.