I've had lots of fun with WASM Python in the browser - a few of my experiments with that are:

- https://lite.datasette.io - my Datasette app in a browser

- https://simonw.github.io/research/pyodide-asgi-browser/datas... is a new, improved version of that using Service Workers that's still a little experimental - notes here: https://simonwillison.net/2026/May/30/pyodide-asgi-browser/

- https://tools.simonwillison.net/micropython runs a MicroPython playground in the browser via WebAssembly

My use-cases for server-side WASM Python are described here: https://simonwillison.net/2026/Jun/6/micropython-in-a-sandbo... - basically I want to offer end-user customization features that run custom code without buggy or malicious code crashing my app or leaking their data.