It appears that the blocking here is of a very different nature than for Opus. Whereas with Opus the blocks seem to be for messages it deems potentially harmful, for Fable, it appears the blocking is simply anything that falls within "topics related to cybersecurity, biology and chemistry, or distillation attempts".

So yes, straightforward biology work will get blocked, because the intention is that any biology work should get blocked. As a scientist, this is perhaps the most useless model I've ever tried.