As someone who works in bioinformatics, and, as such, does a great deal of machine learning, this makes Fable unusable for me as well.
For sure Anthropic should be developing a model without these guardrails for your use case? Kinda like Mythos is only available to certain organizations.
Fable would be unusable for you in a more literal way, since it just directly refuses to answer any query even remotely related to biology