We have a UK client in the healthcare industry who registered the domain clientname.healthcare, and they rapidly found that the NHS imposed regexes which rejected [email protected] emails.

Aside from regexes though, I also think the new TLDs confuse quite a lot of people. [email protected] just doesn't click as an email address as quickly as [email protected], and I'm in tech so I'm sure it's much more confusing for people outside that space.

In fact, that reminds me that we built a site for another client for use inside an exhibition space which was spacename.house and against our advice they put that - without www or https:// - on exhibition panels for use on mobile phones. I am absolutely convinced that most people didn't realise it was a web address.