The National Rifle Association (NRA) describes itself as America’s longest-standing civil rights organization.

That is a specific US-internal stance.

There's a list of organizations that started in the US, ultimately having had to work around the US legal system, in pursuit of their missions:

re Planned Parenthood Global, WikiLeaks, International Campaign to Ban Landmines, Center for Reproductive Rights, selected programs of the Human Rights Campaign Foundation, et al