Related to this is one and only thing I would say I hate about my Framework Laptop 12: its Airplane Mode key.
I keep Fn-lock enabled at all times and use the Fn/LCtrl-swap option in the UEFI just like the one on ThinkPads, but if I ever accidentally hit non-Fn-locked F10 the key code is interpreted by the EC instead of by the OS, so there's nothing I can do in the OS to disable it.
Even worse is that it's adjacent to PrintScrn, so it's the “oh fuck I wanted to take a screenshot and just dropped myself from the match” panic panic panic key.