Thanks for the tip. That does make sense, although I do think having your default CSS-defined font sizes (across your whole app, not just the main content) be a reasonable size should be the first priority.
Also, not having ridiculously oversized margins, like so many 2019-2022 websites trying to look "modern" used to use.
old.reddit.com is one example where the paddings still look good when magnification is set to 150-170% (which I have to do because of the tiny default font size). I think doing it that way but with better readability at 100% zoom, would be a decent solution.