I recently switched back to Homebrew from Nix, and the three big factors in that switch are:

- Brew seems to have better support for the packages it has, compared to Nix where it seems a percentage of packages are not as well maintained,

- Better Mac support; some Nix packages have features disabled on macOS, I think just because the maintainers of this packages don’t have a Mac for testing,

- Better UX.

Obviously I miss the reproducibility of Nix environments and the ability to easily create my own flakes with specific packages, but on the balance, Brew has won me back. (I still like Nix, and FWIW we use Nix at work.)