https://pubs.acs.org/doi/10.1021/acschemneuro.6c00252
In mice. This is a repeating trend in Alzheimer's research, where the amyloid-beta treatment works in the mouse model but not on humans, because the mouse model induces the amyloid-beta issue (mice don't really get Alzheimer's) and then we treat it.
It is a repeating trend in all medical research. However enough does turn out to work in humans that we eventually make useful progress.