I've been using LaTeX for math for over a decade now. I'm pretty happy with it frankly, but there are major pain points in the compilation time and whenever it's time to interface with the language programmatically. Typst is, frankly, awesome in that regard.

However, I really dislike the 'magic' in the math mode syntax, and I think dropping backslashes (more generally, a delineator) for commands was a mistake. Those aren't blockers though, and I think the org is largely making good decisions. I'm really looking forward to the day I can write research in it!

I think all that's remaining is time in the community and stability. Once journals begin accepting it, I know I'll definitely try to submit in it.