Pretty much every single part of Project 2025 is designed to reduce America's standing in the world, not just the anti-science parts of it.

It's a general trend across all authoritarian regimes; it's harder to be authoritarian with lots of international connections, with lots of strength and partnerships.

Autarky, authoritarianism, isolation, all go together (along with weak economies, etc., but the goal isn't to have the biggest amount of pie, the goal is to be able to control all the pie slices and take the biggest portion, even if the pie is far smaller.)