As others have alluded to, I'm not doing this to be anonymous, I'm doing this because companies can't be trusted not to leak my email address. Every real business that knows my real identity (banks, payroll, government, retailers, etc.) gets its own alias.

When an organization invariably leaks my email and I start receiving spam to it, I generate a new one, update my email on record, deactivate the old one, and the spam stops.