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estearumyesterday at 1:05 PM1 replyview on HN

Sure here's one revolutionary new finding in that timeframe: that a person's social/cultural environment affects DNA methylation and gene expression for the rest of their lives.

Here's another one: a person's perception of whether they "are" rural is actually a better predictor of their health outcomes than whether they actually are rural. I.e. two neighbors living side by side in suburban America, the one who perceives themselves to be rural will have dramatically worse outcomes than the one who perceives themselves to be urban/suburban.

These are both potentially useful things to know as we try to eliminate extreme health disparities between Americans.

You seem to think we have all the answers though, so what's the answer? How do we do it?

FWIW, the specific cited research where she's trying to quantify the health impacts of living near pollution sources is actually important for e.g. lawsuits where people try to hold corporations accountable for poisoning their children. Any value in that?


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timryesterday at 1:25 PM

> Sure here's one revolutionary new finding in that timeframe: that a person's social/cultural environment affects DNA methylation and gene expression for the rest of their lives.

This isn't revolutionary. But it's a perfect example.

This is a completely derivative conclusion from something I learned in molecular biology as an undergrad. The only "new" thing here is saying that poor people live in environments, since we've known for literally decades that DNA methylation is affected by environment.

> a person's perception of whether they "are" rural is actually a better predictor of their health outcomes than whether they actually are rural.

OK. Great. I'm poor if I think I'm poor. Roger.

> These are both potentially useful things to know as we try to eliminate extreme health disparities between Americans. You seem to think we have all the answers though, so what's the answer? How do we do it?

I don't know! You tell me how your "potentially useful" information provides a solution. Win me over!

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