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JumpCrisscrosstoday at 1:27 AM1 replyview on HN

> Would you subjectively describe that number as "almost zero"?

Sure. If the only effect were on under-30s, this wouldn’t be a great vaccine. What 5,000 people is good for, however, is confidently measuring decline in a cohort. Zero deaths, even against a baseline of tens, strongly implies this should cross into the tend or hundreds of thousands over the next decades in populations that keep vaccination rates up.


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somenameformetoday at 5:10 AM

Looking at healthcare stuff globally is misleading because of Africa. The ongoing HIV/AIDS epidemic there makes death rates for anything that HIV/AIDS can contribute to highly malinformative. For instance in southern Africa, more than 60% of women with cervical cancer also have HIV. [1]

Oddly enough I can't find exact death rates from cervical cancer paired amongst those who had HIV/AIDS but this [2] hints at it, with 90% of all cervical cancer deaths coming in low/middle income countries, and with the "highest burden" (plurality I guess?) coming from sub-Saharan Africa where rates of HIV are the highest. [2]

[1] - https://pmc.ncbi.nlm.nih.gov/articles/PMC7815633/

[2] - hhttps://www.unaids.org/en/resources/presscentre/featurestori...

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