I agree and disagree, you can't target everything, but most (not shit) devs will target at least Safari - 1 or 2, simply because the iPhone market is too good to miss out on. And Safari being, well, Safari, means targeting that is a pretty safe bet for anything else.
Depends on the region, no one where I work has an iPhone or a current Mac, so stuff gets tested on FF and Chrome, and Safari gets thoughts and prayers. We would test on Safari if it were simple, but alas.