Has anyone done a RCT of D3+K2? K2 seems to be important in the absorption of D3. Another aspect that bothers me with these studies is that we’re simply supplementing the vitamin D, seemingly without measuring the change in blood levels. I took 2000IU (+K2) a day for many years in between testing my blood levels and still had <30ng/ml and had to go up to 5000IU/day. I’d like to see some further study.
TARGET-D is an in-progress study that supplements vitamin D based on blood levels (your idea).
Were you taking hard tablets? And were you taking them with a fatty meal?
Those are both very important. I take a Vitamin D + K2 softgel with a meal that has some fat in it.
> I took 2000IU (+K2) a day for many years in between testing my blood levels and still had <30ng/ml and had to go up to 5000IU/day.
Likewise, 23ng/ml while taking 2000iu/day of dry vitamin-d.
Switched to 5000iu +K2 in MCT oil, -- 8 months later I'm at 64ng/ml.
What I found was that I had to dissolve vit D under the tongue, not immediately swallow it.
K2 is also known to prevent problems with calcium build up which can happen if Vitamin D is dosed too high. I personally would never take Viramin D without K2 alongside it.