The amount of nuclear generation is roughly fixed (minus the refurbishment of three mile) in that region. If you add additional large load to the grid and outbid other demand for that power you are just shifting the load you replaced to other sources, which in PJM region would be mostly gas (new or existing) and delaying the decommissioning of existing base load coal plants. Renewables in that region are unfortunately a small percent of electrical generation.
I do agree that other demands like water consumption are overblown and could be largely regulated to enforce best practices. What infrastructure we are building as a society to meet this load demand is going to be the lasting impact of this generational infrastructure investment and it's looking like that will be mostly fossil fuel based in the near to mid term.
I’m only talking about my local area. I’m not defending the Colossus sites. I don’t live near them.