I've been posting about this including here for years now. I wrote a long post about it a while ago here and on Reddit. At time no one was talking about it, and actually my Reddit post was buried behind tons of others which was frustrating at the time given I had basically shared a partial cure.

Now if you search "reddit eds glp-1" or tirzepatide you'll see tons and tons of long threads of people all saying the same thing - it's the only thing that actually helps.

For me it was something of a miracle, I have two overlapping immune issues and it seems to just turn me into a much more normal, functional person. Including fixing my sleep.

Never was overweight beyond maybe ~15lbs btw when I started or took it, and the effects are 100% not because of just fasting or weight loss. I had tried keto and OMAD before, and been at healthy weight my whole life.

There's a definite auto-immune modulating mechanism and it's so strong it seems better than basically most first-class drugs. Even things like prednisone which are like nuclear weapons don't give me relief like Tirzepatide does.

Btw highly recommend Tirzepatide of the three GLP-1 drugs, for me at least it's by far the most effective and least side effects.

This is why I took it, auto immune related ME/CFS. Works great. I still get PEM but outside of that I get to live a normal life.