My only issue with this was the restriction of "Do not look at any data outside of our working folder" is preventing the tool from doing what it does best. I would have given it access to PubMed to pull the latest research on the subject and validate.

I wouldn't consider Claude itself to be the tool that does a job like this, but the tool that pulls in the best data and gives a supported suggestion. And then go through a number of iterations on where it failed to hone in its assessment.