alt Hacker News> microreactors don't seem to have any inherent disadvantages
They have diseconomies of scale. Some of the costs of a nuclear power plant scale sublinearly with power. Neutron economy is improved in a larger core. Larger turbines are more efficient than smaller turbines. It doesn't take 1000x as many operators to operate a NPP with 1000x the power output.
Is that relevant? The economics of nuclear plants doesn't have anything to do with efficiency as far as I'm aware, the fuel costs are relatively negligible. They can afford to be horribly inefficient if they can get economies of scale producing the plant. So you can use inefficient turbines and have bad neutron economy and it wouldn't change the economics by anything in particular.
You'd also probably find similar issues with diesel generators, but small diesel generators do roaring trade and have great commercial applications.