I kid you not, there was a movie with Sean Connery called "Medicine Man" (1992) with this exact same theme.
https://www.imdb.com/title/tt0104839/?ref_=fn_t_1
In it, Connery finds what looks to be a rare natural cure to all cancer in the Rain Forest (spoiler: not a frog, but equally as weird), and is literally battling the nearby deforesting and bulldozers. For a Sean Connery movie it was bizarre (As a young teen, I saw it in the theaters.. quite a bit less action than a 007 movie but good drama and dramatic Sean Connery acting).
>For a Sean Connery movie it was bizarre
Buddy, if you're trying to tell me it's weirder than Darby O'Gill and the Little People, I am going to need more than Sir Connery in a ponytail.
I've seen the movie several times. In Italian, the title was translated simply as Mato Grosso, which makes it oddly geographically specific. ¯\_(ツ)_/¯
Connery definitely starred in even weirder movies. Have you seen Zardoz?
https://www.imdb.com/title/tt0070948/
https://m.media-amazon.com/images/M/MV5BNmI2NjI2OWYtMzU5NS00...