I would strongly disagree with the idea that 'low-hanging fruit' is gone.
> But knowing how to do those things in the 2000s is not the same as inventing how to do those things or even knowing how to do those things as a well-compensated career before things were so completely consumerized and commoditized.
Two things; First those skills are more useful than you can imagine when you're using commoditized things to do something new and second, it isn't "low hanging fruit to recreate something you can buy anywhere.
If you look at today's software (as an example) we have programs that waste the crap out of resources. Is making them more efficient a win? Yes if you can re-purpose the resources you freed up for other things. I've thought long and hard about things people use "computers" and the "internet" for today that could be built more securely on simpler hardware with ironclad privacy guarantees and more utility. That is a low hanging fruit.
What I'm hearing when I reading your comment is that you feel that all the value has been sucked out of the market and there isn't anything left. And in that I think you'll find that enshittification has polluted the value so much that new opportunities have opened up for unpolluted value. There are many things that are currently "solved" with an existing and and over priced solution which creates opportunities to re-imagine the solution with something less expensive and come in underneath the market. The IBM PC/AT completely displaced minicomputers at small to medium businesses, you can build a PC/AT equivalent today for $6, not $6,000.
The thing here is that 'technology' isn't the same thing as 'value.' Just like knowledge is not the same thing as wisdom. As the author in the linked article writes, it doesn't take a whole lot to stand up a manufacturing line to make a new thing these days, and if that thing has value because it solves a problem, then people will pay to enjoy that value. And to pair that with the earlier metaphor, if you wanted to start a local newspaper (high value) you could with a printing press, some newsprint, and a journalist or two. But without the experience of how newspapers are valuable to their readers, you might be unsuccessful even though you know everything you need to know about writing news stories and printing them.
I'm not trying to be pedantic here, yes there are lots of things going on, and it can seem hopeless, but it isn't. And if you do want to design a high performance CPU you can get a kick ass FPGA to host it for cheap. Variants on RISC-V are pretty impressive and you can make a new one and license it to a chip fab if you choose to. This is WCH's entire business. Don't worry about being the next Tesla or Edison, neither of them knew they were going to be the Tesla or Edison we know today. They were both just trying to create solutions to problems. Look for the problems, think about ways to solve them, and then talk to people who live with those problems day in and day out and see what it might be worth to them to have that problem solved. People love to complain in my experience :-).