Here's an answer for you: we need a new temperance movement.

Sounds pretty ridiculous at first, but that's because people know little of the temperance and progressive movements of the late 19th and early 20th century besides "prohibition failed". There was a whole lot more to it than mere anti-alcohol push, it included labour rights and reform (Upton Sinclair's The Jungle, etc), Anti-trust and anti-monopoly laws, anti-political corruption, consumer protection (food regulation), women's suffrage, etc. The 20th century progressives essentially saw a huge concentration of money and power turning society into a cruel, exploitative machine that ground people up and spat them out. Rampant alcoholism was only one part of it.

A modern version would be different in details but similar overall. Alcohol and cigarettes are not major problems, but corruption, monopoly, and engineered addiction are very real and very problematic. A new temperance movement would be about tackling rampant gabling and addiction (everything from gas station drugs to social media algorithms), political corruption, tech monopolies, misinformation etc.

Big problems need big solutions, but I suspect things will have to get worse before people realize the scale of the problem they're facing.