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m_a_gtoday at 6:28 PM1 replyview on HN

In most countries 4g is the upper limit and it is considered perfectly safe within that limit. So 8 500mg pills in 24 hours.


Replies

nostrademonstoday at 6:33 PM

Yes. 4g is generally considered perfectly safe and is fairly commonplace dosing. 7g can kill you. Hence a therapeutic index of < 2.

This is why you have to be very, very careful. If you're doing 8 500mg Tylenol pills and then you also do 6 doses of DayQuil or Mucinex without realizing it's also acetaminophen, you can end up needing a liver transplant.