After years of dipping into random chapters for reference I read through the first 2.5 volumes sequentially until life got too busy. I plan on gifting the current full set to myself this xmas- but even if you just dip into it like a coffee table book it’s a wonderful read that breaks up tough sections with humor.
For a fun joke, check the index entry for "Royalties, use of" --- it points to a graph which is evocative of the layout of the pipe organ in his home which was funded by TAoCP book sales.