There's kinda a significant difference between bloodletting and blood donation.
For starters, you're not supposed to donate blood when you're sick.
The other being the quantity. A donation is 1-2 pints. Wikipedia lists bloodletting as easily 3 pints [1].
[1]: https://en.wikipedia.org/wiki/Bloodletting#Use_in_the_1600s_...
Although PFAS is helping bloodletting make a comeback https://www.theguardian.com/uk-news/2025/jan/16/bloodletting...