Moscow could only accomplish this with nukes, and only early in the war. By this point Ukraine has dug underground for most of its crucial war-sustaining industry.
Ukraine, well they don't have nukes but as I understand it, much of the USSR's nuclear arsenal was built in Ukraine. I suspect Ukraine could respond tit for tat.
Why can they not use firebombing and other conventional munitions? If they can deliver a nuke surely they can deliver a conventional warhead. That is enough to level an urban area as we see in Gaza.