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jdw64today at 3:22 AM3 repliesview on HN

I read it, and it seems like the core formula is ΔL ≈ ln(1 / HR) × 12.93 years (for U.S. males). It also gives you an easy way to approximate and interpret HR values from health studies, like an HR of 0.90 roughly translates to a little over a year of added life expectancy. Makes it easier to read those papers.

Personally, I found it interesting. But what I'm curious about is this: are there any studies where the lower your exposure to risk, the shorter your lifespan gets?

I've been thinking about this because I recently saw a story about an ultra wealthy guy who tried a reverse aging experiment and ended up with an incurable disease. This person probably had the best diet in the world and received top tier care, so how did he end up with something like that? It makes me wonder, maybe the human body just rejects reverse aging itself. Maybe we're wired to die because that's how species diversify. Just curious.


Replies

Insanitytoday at 4:18 AM

I think there’s just a decent component of “random chance” involved. You can live a healthy life and still die too young, or you can be a lifelong smoker who lives to 90.

When thinking about the impact of behaviour on health, it talks about humans in aggregate, not on an individual level.

krackerstoday at 5:14 AM

>so how did he end up with something like that

Is it not possible that the interventions were the cause of the disease? There's a lot about the body we don't understand, if you're mainlining supplements daily and doing blood transfusions on the regular you're messing around with a delicate biochemical balance.

imInGoodCompanytoday at 5:47 AM

You're thinking of Bryan Johnson. He has autoimmune gastritis, it's not exactly a death sentence.