I try to be open minded about research choices because I have no special knowledge of what will or won’t be important. Left-field discoveries have made profound and positive impacts on many occasions.

I’m having trouble with this one, and am tempted to write it off as playing with mice in a lab. The extrapolation to human conditions is hyperbolic, maybe worse.

Given the number of people with continuous glucose monitors and activity tracking watches in the world, why not study that data directly? Causation by activity would be more apparent, more relevant and more significant (if present) wouldn’t it?