I first learned of kratom in the last year from Elijah Lemard

https://www.youtube.com/watch?v=0z5ixJIqbGY&t=267s

He's an odd guy who likes to investigate some really dodgy stuff. And I suspect many here on HN would appreciate him.

That led to 7-OH showing up in my feed at some point. In a nutshell, it's the strongest of the active compounds in the kratom plant, that binds to opioid receptors. 7-OH is the marketing name for the alkaloid 7-hydroxymitragynine that is being refined from kratom. It's not clear to me if it's simply extracted, or as some quick research suggests, it might also be a chemical alteration of the more commonly occurring compound in kratom mitragynine.

Anyway, this stuff looks super habit forming, and, of course, the refined version is that much more addictive.