In this context, something fascinating is https://en.wikipedia.org/wiki/Thermal_grill_illusion
You can artificially induce a burning pain sensation using alternating strips of mildly warm and mildly cold.
Here William Osman of all people builds one of these and uses it on his friends
Will this help to better therapy for hyperhidrosis? I hope
I have CNS and nerve damage from covid and my hands are basically my regulators now
I get Raynauds syndrome even in the summer
Basically if my hands are warm, I am warm, if my hands are cold my entire body is cold
always wanted to try this Sony cooling device
* https://www.sony.com.hk/reonpocket/2026/en/
but wrist heater/cooler might also work
We still don't know how, like from a physics point of view, thermoreceptors detect temperature.
> “These findings could help explain what happens when the body’s thermoreceptors become impaired in ageing and disease.”
> ...this new understanding of the body’s thermoreceptors could inform treatments for people struggling with thermal dysfunction.
It would be amazing if this research also led to a treatment for the rare symptom of temperature reversal caused by ciguatera fish poisoning (ciguatoxin neurotoxins) overstimulating one's nerves. I am not personally afflicted but have friends who have been; one is still dealing with various symptoms many years later.