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estearumyesterday at 6:08 PM1 replyview on HN

The first paper shows no evidence of any effect from Tylenol...? But yeah seems like lots of support for the ibuprofen protective effect, interestingly.


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eth0upyesterday at 6:41 PM

If you do start munching on advil; note there are rumors, by medical researchers, case reports, and more, that if you dig beneath the shiny surface to find, do show a lot of compelling data for GI damage, heart risk and other serious side-effects. And depending on how fair one wants to be with 'evidence' -- almost all wording describing NSAIDs as "protective", uses easy-to-miss but distinct qualifiers such as "potential" and other such vague 'maybe'-equivalents that alone have been used to suppress and dismiss many other...potential medicines. Sometimes, conclusive just means inspired. And sometimes ambiguity means certainty, depending on levels of inspiration involved.

Of course, one might pause for a moment to consider just how potential the alluded benefits really are with ibuprofen, and ask why doctors aren't recommending it for mental health, or as a general health product. But that might point to the peculiar fact that there is substantially more evidence suggesting risk over health benefits, and the benefits really depend on what one wants to see. There is a reason it's not marketed as a health product, but with the way it's framed, it should be, nu? I mean, potential benefits sells a lot of snake oil and lowfat yogurt. Why not advil and acetaminophen?

And by similar logic used to dismiss acetaminophen here as a health risk, eg because there's no link with autism/ADHD it's safe; why not apply the same logic to opiates? We could just say opiates do not directly cause, eg , parkinsons, or AIDS, therefore it's safe for babies. Myself, I never correlated acetaminophen with autism/ADHD, but I know it has more side-effects than listen on the bottle.

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