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JoshGlazebrooktoday at 4:10 AM1 replyview on HN

Next up is the lp(a) lowering drugs still in trials.


Replies

nwah1today at 4:48 AM

Yes, exciting stuff.

Not to mention the gene-therapy version of the same PCSK9 inhibition pathway called VERVE-102 which Eli Lilly is putting through human trials as we speak.

I imagine that stacking the LP(a) antisense therapy with a PCSK9 inhibitor, and/or a statin or Nexlizet would probably lower odds of heart disease death by two to three orders of magnitude. But I guess there isn't solid mortality data to say for sure.