I have familial hypercholesterolemia and none of that makes any difference. In fact 2 of my siblings and both my daughters have it too. My youngest sister had a stroke at 24 because of it.
Diet, statins, etc can't get us in healthy ranges and PCKS9 inhibitors is literally the only thing that moves the needle. I'm on Repatha, one of the injectable inhibitors, statins and Ezetimibe to manage it.
Needless to say I am super happy about this news, especially if it is affordable.
Really hopeful that Verve 102 passes trials and becomes generally available.