I've used LLMs to bootstrap successfully in a decent amount of things at this point.

Anyone trusting AI as the single authoritative source of information is stupid - but this follows from the fact that trusting anyone as a "singular point" as a source of information is stupid. You corroborate, you intervene on the world to test your mental model, you discuss with other people. That's what learning is. I've never learned from start to back to a textbook before as the single source of information (besides one philosophy of science textbook; in which I spent a month digging around adjacent fields, and then it just so happened that that one textbook synthesized every piece of information I looked up, and it was mostly a consolidating review).

If your study pre-supposes certain courses of action and artificially constrains the action space for the sake of "reproducibility", you may get a result, and a "scientifically rigorous one". But it's not going to say anything about reality in any meaningful way. While anecdotes and the complexity of real life isn't "science" (in that it's a controlled, repeatable, interventional experiment that's subject to a community of critics who want to hold you up to standards of rigor), there's far more truth in how people actually proceed and engage with these tools.