Itanium had all sorts of specialized machinery so that you could issue a load that's required in the future, and then keep chugging away at the instruction stream, similar to what an OoO processor does with it's reordering logic.
One example was "advanced loads" which allowed you to issue a load as soon as you knew the address, even in the face of potential pointer aliasing in the future, and then later complete the load when you actually hit a data dependency that requires it. https://devblogs.microsoft.com/oldnewthing/20150805-00/?p=91...
Another example is "speculative loads" which lets you issue a load before you even know if it's valid, such as unrolling a loop for an array that you don't know if is a multiple of the unrolled loop chunk length (and therefore might trap with a page fault if fully resolved). https://devblogs.microsoft.com/oldnewthing/20150804-00/?p=91...
These worked well for “known” intra-task pointer aliasing situations, but if you don’t know what will be in cache due to preemption of any kind, you still don’t know how many cycles the speculative loads will take, so you get the same stall risks across a dependency hazard.