The two largest vtuber agencies/companies are publicly traded in Japan.

https://finance.yahoo.co.jp/quote/5253.T?term=2y

https://finance.yahoo.co.jp/quote/5032.T?term=2y

The stock prices are not great all things considered- I think that the vtuber audience needs something new/different to broaden beyond it's current market base AND I think investors would rather put money into AI related stocks than IP/vtuber related stocks.