Not with NixOS. ld.so is tied to a version of glibc, in ways that can be subtly incompatible. And nixos can have multiple glibc version installed on a single machine.
Besides, it allows for upgrades/downgrades to be done in a way that's much less error-prone.
>in ways that can be subtly incompatible
There is much more value to be had in making glibc properly backward compatible so you can have a single one that can be used with everything than trying to make it so that you can swap everything around, creating extra complexity and compatibility risks.
"ld.so is tied to a version of glibc" is such a horrible GNUism.