They won't have untyped dependencies for situations where someone used Scriptc as a way to build a fast binary executable for some custom-written TypeScript, which was the first use-case that came to mind for me.

Being able to build small, fast binaries without writing them in C or Rust - if you're already fluent in TypeScript - seems like a valuable capability.

Devil's advocate - this is for the backend. You get to control your dependencies there, and I'd say Vercel controls its own stack, so they can replace deps as they go by submitting patches/slopforking projects to remove incompatible features.