alt Hacker NewsThere's an emerging practice of using Q4 quants and Q8 KV cache for local inference. At that point you can run both Qwen3.5-122B-A10B (my personal choice on Framework Desktop 128gb) and Laguna-S-2.1.
Now whether that's good enough for one's use-case remains to be determined. You can also get more out of those (local models and quantizations) if you further tweak the harness you use them with, but tbh this is where it gets too much work (at least for me and the time I have available).
> emerging practice of using Q4 quants and Q8 KV cache for local inference
That's not an emerging practice, it's a tested strategy that is these days only used as a last resort by those desperate to fit a model in memory. Some models do better than others, but generally the model quality suffers greatly under those conditions.