Artificial intelligence.

If humans are machines executing on some medium eventually it will be possible to emulate them on some other medium. Believing otherwise requires some essentially religious convictions on the existence of the soul or similar.

The pacing and the prolonging, obviously!

Technological changes to economic conditions in general are not possible to opt out of forever. I'm not an AI accelerationist myself, because I think there are severe risks beyond the merely economic, but the auto industry is a good example of where many countries are engaging in what one might call "EV accelerationism". In principle you don't have to, it's possible to let them roll out only to the extent that the market naturally demands, but if you know internal combustion engines will become a niche hobbyist thing by 2050 there's a lot of value in making that transition faster and intentional.

That all persons doing intellectual work die of hunger as they cannot find a job. At least that's how I understand what the parent commenter is implying. They say that all people doing intellectual work better die quickly so they don't suffer a long 'transition period' to inevitably being dead of hunger.