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jmcgoughtoday at 5:05 PM2 repliesview on HN

Half of people with Alzheimer's carry at least one APOE ε4 allele. However, a full quarter of the population carries that mutation, and most carriers never go on to develop Alzheimer's. Lifestyle matters a lot here.

This kind of misdirection is not helpful for educating people on changes they can make now to reduce their risk, rather than waiting for a silver bullet. Alzheimer's research is well-funded in the US as the octogenarians running our congress are personally invested in it.


Replies

detourdogtoday at 6:39 PM

My understanding is that there are forms of dementia more tied to genetics than "Alzheimer's". One that has links to genetics is Frontal temporal Dementia.

bpodgurskytoday at 6:11 PM

To the extent that lifestyle helps, which is not zero, you need to exercise. "Become a cabbie" is NOT an intervention that is going to help whatsoever.

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