If anyone wants to go down a rabbit hole, go search for topics around fructose corn syrup, visceral fat and artery plaque. It can play a substantial role in vascular health. I'm not a doctor but there's a bunch of studies posted online about this and my doctor also agreed when I asked him about it.

Avoiding fructose corn syrup is a really good idea. It's in a ton of sugary drinks. It really messes with inflammation in your body and your liver materializes it in a very similar way as alcohol. Basically both are bad and can cause similar issues.

For me personally I walk a few miles a day for 15+ years and I'm in ok shape. Cutting out Arizona iced tea (has a lot of fructose corn syrup) has made a material difference in how my body operates, I used to drink 1-2 cans a day for a while. Nowadays going 18 hours without food is no problem, I don't have mid-day tired spikes and I didn't change what I eat. I can't explain it but it feels like it reset something.

When I've been on vacation in other countries outside of the US for a few weeks, I noticed the same thing (less hungry, more energy, etc.) and a commonality there is I also didn't drink large amounts of fructose corn syrup. There's a lot of variables I'm sure but I can say I feel a difference for the better after stopping and I've now repeated these feelings when doing normal things locally.