Spear phishing isn't a real problem. Competent organizations have already implemented sufficient defenses and controls, regardless of whether the attacker is a human or LLM. Idiots will continue getting scammed but that's nothing new. I expect that many small businesses and local governments will be essentially forced to outsource their IT infrastructure to large vendors that can maintain hardened systems appropriate to the escalating threat level.

(Nuclear waste isn't an actual problem either. For civilian powerplants the highly radioactive waste can generally be stored indefinitely at the reactor site.)