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antonytyesterday at 4:43 PM2 repliesview on HN

Were all the other vaccines "well understood" when they were initially rolled out en masse? Not a rhetorical question, I genuinely don't know the history.

I don't really understand what people's expectations were for a new vaccine intended to combat an ongoing global pandemic.


Replies

kansfaceyesterday at 7:05 PM

Several labs that manufactured the original polio vaccine shipped the live virus - ie, we just injected kids with polio. Low double digits of people (kids?) died, a few hundred were paralyzed, etc. Later vaccines also had the same problem, but at very low rates (1 in millions maybe).

gaddersyesterday at 4:46 PM

I don't think they were developed in less than 6 months, and probably had more testing (and have had far more since).