With a desktop its usually possible from the network setting GUI? Worked like that last time I needed to use a VPN for access to a corporate network.
Some of the NetworkManager VPN plugins have weird side-effects. Like the one for OpenVPN force-disables split tunnel configurations and there's no way to turn that off, meaning that all traffic routes through the VPN even if you'd rather only send stuff for certain destination addresses through.
Based on the experience that I (and other coworkers, including on other distros) had, whatever configurations our VPN needed did not seem to work out of the box on network manager.